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KMID : 0374019860090020083
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Ewha Medical Journal
1986 Volume.9 No. 2 p.83 ~ p.98
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An Experimental Study on the Condition of Irradiation and the Skin Reaction by 6 MV X-ray
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李京子/Lee, Kyung Ja
李丁植/Rhee, Chung Sik
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Abstract
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The maximum ionization point of supervoltage Xray radiation modality is moved to subcutaneous tissue by the build up effect, as the result, the surface dose of the skin is decreased.
It is necessary to measure the accurate dose distribution of supervoltage Xray radiation modality and determine its biological effect on the skin in order to increase the effect of radiation therapy.
By using 6 MV Linear accelerator, the absorbed dose of the skin and subcutaneous tissue was determined by physical aspect in relationship of 6 MV Xray´ and tissue and a uniform formula was developed.
For the experiment, guinea pigs were divided into 3 groups. A single irradiation group was irradiated with 10 -60Gy, and a single irradiation group with 0.5cm, 1.0 cm and L5cm bolus was irradiated with 10 40Gy, and fractionation group was irradiated with 20Gy by 3 fractionation for 1 week and with 30Gy, 2, 3, 5 fractionation for lweek and 2 weeks respectively.
The results were as follows
1) The absorbed dose of 6MV X- ray was increased depending on the depth of skin and its maximum point was 1.5cm from skin surface.
2) The skin score by a single dose irradiation was proportionally increased by the dose and D,.,, dose at the point of skin score 1.5 was 25Gy.
3) The maximum skin reaction by a single dose irradiation was developed about 24th day after irradiation and generally the skin reaction was developed earlier in higher dose.
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